http://zulko.github.io/moviepy/index.html

MoviePy is a Python module for video editing, which can be used for basic operations (like cuts, concatenations, title insertions), video compositing (a.k.a. non-linear editing), video processing, or to create advanced effects. It can read and write the most common video formats, including GIF.

https://wiki.python.org/moin/AudioVideo

Audio and Video

Some Python-based projects related to audio and video. See also Screencasting.

Audio/Music Editors

Jokosher – a complete application for recording, editing, mixing and exporting audio
See also PythonInMusic for more projects.

Audio/Music Players

FUPlayer – a music player with management and CD ripping/burning capabilities
Listen – an audio player with music management features
Quod Libet – an audio player with scalable management of music collections (more than “a mere 10000 songs”)
TimPlayer – a PyGTK based music player using GStreamer (see http://creationix.com/OpenSource/TimPlayer/)
Libraries and Frameworks

GStreamer – an audio/video playback framework – has Python bindings
MLT – an open source multimedia framework, designed and developed for television broadcasting – has Python bindings
MoviePy – a Python library for script-based movie editing (cuts, concatenations, text insertion, non-linear editing)
See also Audio for details of Python audio libraries.

Media Centres

Elisa – an open source cross-platform media centre solution
Freevo – Linux multimedia jukebox
Streaming

Boxtream – a mobile and autonomous audio and video streaming and recording studio (uses GStreamer)
Flumotion – a streaming media server (uses GStreamer)
Video Editors

OpenShot – an open source video editor, written in Python and based on MLT and PyGtk
Pitivi – an open source video editor, written in Python and based on GStreamer and GTK+